heat shock response การใช้

• The hsp90 gene product is involved in the " Drosophila " heat shock response.
• The "'Hsp90 cis regulatory element "'is an translational efficiency during the heat shock response.
• Importin ? has also been implicated in the development of heat shock response in " Drosophila " embryos.
• In the Sulfolobus solfataricus ", for example, a vapBC gene cassette is thought to regulate heat shock response.
• There are many biochemical consequences to the heat shock response within the cell, including slowed cell division and increased sensitivity to ionizing radiation therapy.
• BiP protein expression has been found to be significantly enhanced by the heat shock response due to internal ribosome entry site ( IRES )-dependent translation.
• He later focused his research on " Drosophila " ( fruit flies ), in particular the genetics and biochemistry of the heat shock response.
• This kinase has been shown to be involved in many different cellular functions, such as apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis.
• Its role in heat shock response presents it as a target for treating related diseases like spinal and bulbar muscular atrophy ( SBMA ) and amyotrophic lateral sclerosis ( ALS ).
• This alteration may, in some environments, help these " Candida " species by inducing a permanent stress response, a more generalized form of the heat shock response.
• Like GSTP, GSTM1 interacts with its partner in the absence of oxidative stress, although ASK1 is also involved in heat shock response, which is likewise prevented during ASK1 sequestration.
• Recent research suggests that the topical antimicrobial zinc pyrithione is a potent heat shock response inducer that may impair genomic integrity with induction of PARP-dependent energy crisis in cultured human keratinocytes and melanocytes.
• While this nuclear import process does make up the majority of the functional role of importin ? proteins, several other important functions have been shown to be mediated by importin ?s including gametogenesis, development, heat shock response, protein degradation, and viral pathogen infection.